Relapse in ovarian cancer is common even though platnium based chemotherapy is efectve as adjuvant treatment. If progression free survival is more than one year platnium based chemotherapy can be repeated, which is usually given as three weekly regime. Studies has shown that weekly cisplatn with oral etoposide has shown beter response rate. A lady of 60 year who presented with relapse ovarian cancer, afer two years of primary treatment, responded dramatcally to weekly cisplatn and daily oral etoposide regime.Key Words: Chemotherapy, Ovarian cancer.